From ambivalent to divalent

From ambivalent to divalent

Despite decades of research on the effects of zinc in infectious diarrhea, there is surprisingly little consensus on how zinc works (or even if it works), on whether zinc’s effects are pathogen-specific, and what patient populations are most likely to benefit from zinc supplementation. Some recent articles focus on the growthpromoting effects of zinc on the pathogen itself, leading the reader t...

Ambivalent jew

Ambivalent antihistamines.

-In mice with a transplantable mammary carcinoma, treatment with the prostaglandin-synthesis inhibitors flurbiprofen or indomethacin produced various beneficial effects. Survival time after excision of the transplanted tumour was increased, particularly when the drugs were given with the chemotherapeutic agents methrotrexate and melphalan, and there were more disease-free survivors. The combine...

Ambivalent Dopamine

Many of animal behaviors can be considered as the end product of the motivation to maximize benefits and minimize costs to the animal. Through intensive investigation based on psychopharmacological manipulations , dopamine in the mammalian nucleus accumbens (NAcc) has been implicated to play a key role in multiple aspects of moti-vational control of behaviors. However, the exact mechanism by wh...

Uronate isomerase: a nonhydrolytic member of the amidohydrolase superfamily with an ambivalent requirement for a divalent metal ion.

Uronate isomerase, a member of the amidohydrolase superfamily, catalyzes the isomerization of D-glucuronate and D-fructuronate. During the interconversion of substrate and product the hydrogen at C2 of D-glucuronate is transferred to the pro-R position at C1 of the product, D-fructuronate. The exchange of the transferred hydrogen with solvent deuterium occurs at a rate that is 4 orders of magni...